Aspirin low dose (75 mg/day) can lessen the risk of developing colon cancer by 24 percent and deaths by a 35 percent, according to the study. Daily low doses of Aspirin are already suggested for patients at threat of a heart attack or a stroke by many doctors. In developed countries, colon cancer is the 2nd most common cancer with around one million new cases and 6,00,000 deaths worldwide annually.
Aspirin high doses have been found to stop colon cancer but can be dangerous as it sometimes causes bleeding and stomach problems. As Aspirin restrains an enzyme named COX-2 which encourages cell propagation in colorectal tumors, it is supposed to have a preventive effect. Rothwell said, “Anyone with any risk factors such as a family history [of colon cancer] or a previous polyp should definitely take Aspirin.”
In Britain and Sweden, trials are conducted on the cardiovascular impacts of aspirin in the 1980s or early 1990. The results were the people who took low dose of Aspirin daily for around six years their 24 percent risk of colon cancer is decreased and 35 percent risk of dying from the disease is also decreased. European baby aspirin of 75 milligrams and regular aspirin 300 milligrams are used in the studies. Across the trials, these results were reliable and at a dose of aspirin of 75 milligrams a day.
The researchers noted that any advantage of Aspirin high doses did not appear. High doses of Aspirin over a long period can annoy the stomach, intestines and bowel, causing lesions and major bleeding. Compared as higher doses of Aspirin, daily 75 mg is effective in preventing disease. Aspirin works by obstructing effects of proteins that stimulate inflammation and are linked to cancers including those of the breast, stomach, esophagus and colon.
Benamouzig said that how aspirin might work to reduce the risk of colorectal cancer is not fully known, but it may be due to aspirin’s ability to reduce inflammation. It is concluded by the researchers that the lowest dose of aspirin may help to protect against colorectal cancer and it must be taken frequently for one year before the result is obvious and that protection increases for up to 10 years.
Video of Insidermedicine In Depth – September 16, 2010 – Aspirin May Help Prevent Colorectal Cancer from youtube: